Proteomic Grade Detergent Solutions (10%)

Many commercial grade detergents contain elevated levels of sulfhydryl oxidizing agents, peroxides, salts and carbonyl compounds (Figure 1). The proteins that are isolated with these detergents are highly susceptible to contaminating peroxides and carbonyls. The peroxides will oxidize proteins and the carbonyl groups will form Schiff's bases with the proteins that interfere with a protein's structure.
 
Our Proteomic Grade Detergent Solutions contain reduced peroxides and carbonyl compounds (Figure). In addition, the detergents have less than 50µS conductivity. These detergents are offered as 10% aqueous solutions, sealed under inert gas and are suitable for protein applications. These non-ionic detergents are suitable for isolating membrane-protein complexes.
 
We offer a selection of widely used Proteomic Grade Detergent Solutions. The aldehyde and peroxide levels are <100µM and <50µM respectively with a conductivity of <50µS.
For further details on the Proteomic Grade Detergents available, view the specific detergents in the Proteomic Grade Detergent section.