Tube-O-DIALYZER™

Small sample dialysis has become a routine and popular technique in life science research. Today's major concern with dialysis devices is the loss of precious samples, due either to leaking or precipitation of samples during dialysis. A common cause of sample loss is due to the fragile dialysis membrane being accidentally pierced with a sharp object, such as a needle. A second concern is the efficiency and rate of dialysis. We manufacture a unique dialysis device that allows efficient dialysis and 100% sample recovery, even if your sample precipitates.


The unique tube format of Tube-O-DIALYZER™ allows for easy handling and manipulation. For sample recovery, just place the Tube-O-DIALYZER™ in a centrifuge and spin your sample to the bottom of the tube, ensuring 100% sample recovery, even if precipitation occurs (see figure 1).

The unique tube format also allows for easy sample loading, as simple as transferring your sample to a microcentrifuge tube. Tube-O-DIALYZER™ does not require the use of specialized loading devices or costly syringes and hazardous needles.

Tube-O-DIALYZER™ comes in two ideal sizes; the Micro unit allows efficient dialysis of 20-250µl samples and the Medi unit is optimized for 200µl-2.5ml samples. Both sizes are available with membranes with molecular weight cutoff (MWCO) of 1kDa, 4kDa, 8kDa, 15kDa and 50kDa.

Tube-O-DIALYZER™ are available in packs of 50 each or as a mixed pack of 25 Micro and 25 Medi. Each Tube-O-DIALYZER™ is supplied with 6 appropriately sized floats and Tube-O-DIALYZER™ storage caps to allow storage of dialyzed samples.

A graph representing the fast and highly efficient dialysis rate of the micro Tube-O-DIALYZER™ is shown in Figure 2. 100µl 5M NaCl was dialyzed against one liter deionized water. Samples were taken at specific times, diluted in deionized water and the conductivity was measured. The graph demonstrates the fast efficiency of Tube-O-DIALYZER™, with 50% NaCl removed within 10 minutes.