A2A (Adenosine receptor A2A)

A2A (Adenosine receptor A2A)
G-Biosciences offers full length, highly purified membrane proteins (GPCRs, Ion Channels, Transporters, Receptors and Viral Proteins) for research in antibody development, vaccine formulation and/or drug discovery.  

A unique native isolation process was used to purify these integral membrane proteins with the highest purity levels while keeping their structural and functional integrity (no refolding or mutagenesis). This process conserves the functional and structural integrities of the targets/antigens. This has a significantly beneficial impact on the quality of the protein and on the success of the proteomics and drug discovery applications.

A2A (Adenosine receptor A2A) is a class A GPCR involved in regulating myocardial blood flow/hypertension, the regulation of glutamate and dopamine release. 

A2A is a good therapeutic candidate for insomnia, pain, depression, drug addiction and Parkinson’s disease.

Features
  • No refolding
  • No mutagenesis/truncation/fusion
  • Striking stability improvement
  • High purity
  • Maintain functional and structural integrities
Protein information
  • Class: GPCR Class A
  • Affinity Tag: His/Strep (both N-terminal)
  • Origin: Human 
  • Theor. MW: 47.7 kDa
  • Accession#: P29274 (UniProt)
Protein production
  • Purity: >90%
  • Concentration: Up to 5mg/ml
  • Expression system: Sf9 insect cells (baculovirus)
  • Purification: Immobilized Metal Affinity Chromatography
  • Activity: Confirmed by radiobinding assay
  • Storage conditions: Store at -80°C

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Protocol
786-1408
786-1409
Catalog Description Size Price(USD) Qty
786-1408
A2A (Adenosine receptor A2A) 10 µg
$1,671.00
786-1409
A2A (Adenosine receptor A2A) 50 µg
$7,711.00