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Immobilized Pepstatin (3 Citations)

G-Biosciences Immobilized Pepstatin is for the purification of cathepsins, pepsin, bacterial aspartic proteases, HIV proteases and other molecules that bind pepstatin. 

 

Pepstatin is isovaleryl-Val-Val-AHMHA-Ala-AHMHA where AHMHA= (3S, 4S)-4-amino-3-hydroxy-6-methyl-heptanoic acid and is a potent inhibitor of various aspartic proteases, including cathepsin D, renin, pepsin, bacterial aspartic proteases and HIV proteases.

 

The resin consists of 6% beaded agarose that is covalently coupled to pepstatin through a diaminodipropylamine spacer arm and has a binding capacity of 1-2mg pepsin per millimeter of settled resin.
 

 

Features

  • Capacity: 1-2mg pepsin/ml resin
  • 6% beaded agarose
  • Diaminodipropylamine spacer arm

 

Applications

  • Purification of cathepsins, pepsin, bacterial aspartic proteases, HIV proteases and other molecules that bind pepstatin
Protocol
786-789
Material Safety Data Sheet
786-789
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