Brefeldin A
Brefeldin A is an antibiotic derived from Penicillium brefeldianum. It is an anti-cancer agent which disrupts protein transport and causes apoptosis of tumor cells. Brefeldin A disrupts the function of the Golgi apparatus and blocks Golgi-COPI activity. It has been shown to induce apoptosis in leukemia cells and colon cancer cells.
| CAS # | 20350-15-6 |
|---|---|
| MW | 280.36 g/mol |
| Grade | Molecular Biology Grade |
| Storage | Store at 4°C. |