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C-Reactive Protein/CRP
Protein Specification
Description Recombinant Human C-Reactive Protein is produced by our E.coli expression system and the target gene encoding Gln19-Pro224 is expressed with a 6His tag at the C-terminus.
Alternate Names C-Reactive Protein; CRP; PTX1
Accession No. P02741
Amino Acid Range Gln19-Pro224
Tag C-6His
Species Human
Source E.coli
Background C-reactive protein (CRP) belongs to the pentaxin family. CRP is a secreted protein found in plasma. It can binds two calcium ions per subunit.CRP can promotes phagocytosis, bacterial capsular swelling, complement fixation and agglutination through its calcium-dependent binding to phosphorylcholine which expressed on the surface of dead or dying cells. It can activate the complement system via the C1Q complex. CRP can interact with DNA and histones. In addition, CRP may scavenge nuclear material released from damaged circulating cells.
Purity Greater than 95% as determined by reducing SDS-PAGE.
Product Form Lyophilized
Formulation Lyophilized from a 0.2 μm filtered solution of 20mMTris, 2MUrea, pH 8.0.
Entotoxin Levels Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Reconstitution Dissolve the lyophilized protein in distilled water.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping The product is shipped at ambient temperature.

Material Safety Data Sheet
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