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BAN0296

BAN0296
  • Gene/Protein: Q9Y4Z0
  • Product Description: GRP/LSM4
440.0000
Price in reward points: 440

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GRP/LSM4
Protein Specification
Description Recombinant Human U6 snRNA-Associated Sm-Like Protein LSm4 is produced by our E.coli expression system and the target gene encoding Met1-Gln139 is expressed with a 6His tag at the N-terminus.
Alternate Names U6 snRNA-Associated Sm-Like Protein LSm4; Glycine-Rich Protein; GRP; LSM4
Accession No. Q9Y4Z0
Amino Acid Range Met1-Gln139
Tag N-6His
Species Human
Source E.coli
Background U6 snRNA-associated Sm-like protein LSm4 (LSM4) is a member of the snRNP Sm proteins family. Sm-like proteins contain the Sm sequence motif and are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing. LSM4 forms a heteromer with a donut shape. The complexes are involved in various steps of RNA metabolism. LSM4 binds specifically to the 3-terminal U-tract of U6 snRNA. LSM4 contributes RNA protein interactions and structural changes which are essential during ribosomal subunit assembly.
Purity Greater than 90% as determined by reducing SDS-PAGE.
Product Form Lyophilized
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM TrisHCl, 100mM NaCl, 1mM DTT, pH 8.0 .
Entotoxin Levels Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Reconstitution Dissolve the lyophilized protein in distilled water.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping The product is shipped at ambient temperature.
Datasheet

Material Safety Data Sheet
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