menu
Your Cart

BAN1100

BAN1100
  • Gene/Protein: P17516
  • Product Description: Aldo-keto Reductase 1C4/AKR1C4
Aldo-keto Reductase 1C4/AKR1C4
Protein Specification
Description Recombinant Human Aldo-Keto Reductase Family 1 Member C4 is produced by our E.coli expression system and the target gene encoding Met1-Tyr323 is expressed with a 6His tag at the N-terminus.
Alternate Names Aldo-Keto Reductase Family 1 Member C4; 3-Alpha-HSD1; 3-Alpha-Hydroxysteroid Dehydrogenase Type I; Chlordecone Reductase; CDR; Dihydrodiol Dehydrogenase 4; DD-4; DD4; HAKRA; AKR1C4; CHDR
Accession No. P17516
Amino Acid Range Met1-Tyr323
Tag N-6His
Species Human
Source E.coli
Background Aldo-Keto Reductase 1C4/AKR1C4 is a member of the aldo/keto reductase family that consists of more than 40 known enzymes and proteins. AKR1C4 has highly expressed in Liver. It can catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. AKR1C4 catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-α-Androstan-3-α,17-β-diol (3-α-diol). In addition, AKR1C4 also has some 20-α-Hydroxysteroid Dehydrogenase activity.
Purity Greater than 90% as determined by reducing SDS-PAGE.
Product Form Liquid
Formulation Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0.
Entotoxin Levels Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Storage Store at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles.
Shipping The product is shipped on dry ice/ice packs.
Datasheet

Material Safety Data Sheet
English_US
Danish
Dutch
English_UK
French
German
Spanish
Norwegian
Portuguese
Finnish
Swedish
Polish

Write a review

Note: HTML is not translated!
Bad Good
Captcha

CONNECT WITH US