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BAN1189

BAN1189
  • Gene/Protein: P00352
  • Product Description: Aldehyde Dehydrogenase 1-A1/ALDH1A1
285.0000
Price in reward points: 285

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Aldehyde Dehydrogenase 1-A1/ALDH1A1
Protein Specification
Description Recombinant Human Aldehyde Dehydrogenase Family 1 Member A1 is produced by our E.coli expression system and the target gene encoding Met1-Ser501 is expressed with a 6His tag at the N-terminus.
Alternate Names Retinal Dehydrogenase 1; RALDH 1; RalDH1; ALDH-E1; ALHDII; Aldehyde Dehydrogenase Family 1 Member A1; Aldehyde Dehydrogenase Cytosolic; ALDH1A1; ALDC; ALDH1; PUMB1
Accession No. P00352
Amino Acid Range Met1-Ser501
Tag N-6His
Species Human
Source E.coli
Background Aldehyde Dehydrogenase Family 1 Member A1 (ALDH1A1) is a cytoplasmic enzyme that belongs to the Aldehyde Dehydrogenase family. ALDH1A1 is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties and subcellular localizations. ALDH1A1 is the main cytosolic isoform, which has a lower affinity for aldehydes than the mitochondrial enzyme. ALDH1A1 binds free retinal and cellular retinol-binding protein-bound retinal. It can convert/oxidize retinaldehyde to retinoic acid.
Purity Greater than 95% as determined by reducing SDS-PAGE.
Product Form Liquid
Formulation Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, pH8.5.
Entotoxin Levels Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Storage Store at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles.
Shipping The product is shipped on dry ice/ice packs.
Datasheet

Material Safety Data Sheet
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