menu
Your Cart

BAN1499

BAN1499
  • Gene/Protein: P97290
  • Product Description: Serpin G1/Serping1/C1nh
440.0000
Price in reward points: 440

Available Options

Serpin G1/Serping1/C1nh
Protein Specification
Description Recombinant Mouse Serine Protease Inhibitor-clade G1 is produced by our Mammalian expression system and the target gene encoding Ala20-Gly504 is expressed with a 6His tag at the C-terminus.
Alternate Names SERPIN G1;Plasma protease C1 inhibitor;C1 Inh;C1 esterase inhibitor;C1-inhibiting factor;Serping1;C1nh
Accession No. P97290
Amino Acid Range Ala20-Gly504
Tag C-6His
Species Mouse
Source Human cells
Background SERPIN G1 is a member of the serpin family, The C-terminal serpin domain is similar to other serpins, and this part of C1-INH provides the inhibitory activity. SERPIN G1 is involved in the inhibition of the complement system to prevent spontaneous activation. SERPIN G1 may play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. SERPIN G1 prevents the proteolytic cleavage of later complement components C4 and C2 by C1 and MBL. SERPIN G1 is a very efficient physiological inhibitor of FXIIa, plasma kallikrein and fXIa, and could inhibit chymotrypsin and kallikrein. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases in the C1 complex of classical pathway of complement. Activation of the C1 complex is under control of the C1-inhibitor.
Purity Greater than 95% as determined by reducing SDS-PAGE.
Product Form Lyophilized
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0.
Entotoxin Levels Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Reconstitution Dissolve the lyophilized protein in distilled water.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping The product is shipped at ambient temperature.
Datasheet

Material Safety Data Sheet
English_US
Danish
Dutch
English_UK
French
German
Spanish
Norwegian
Portuguese
Finnish
Swedish
Polish

Write a review

Note: HTML is not translated!
Bad Good
Captcha

CONNECT WITH US