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BAN1887

BAN1887
  • Gene/Protein: P31151
  • Product Description: S100A7
315.0000
Price in reward points: 315

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S100A7
Protein Specification
Description Recombinant Human Protein S100-A7 is produced by our E.coli expression system and the target gene encoding Met1-Gln101 is expressed.
Alternate Names Protein S100-A7; Psoriasin; S100 calcium-binding protein A7; S100A7; PSOR1; S100A7C
Accession No. P31151
Amino Acid Range Met1-Gln101
Tag No Additional Protein Tag
Species Human
Source E.coli
Background S100A7 is a 11-12 kDa member of the S100 family of EF hand calcium binding proteins. Human S100A7 shares 32% amino acid sequence identity with mouse S100A7A, the closest related protein in mouse. It is acetylated at the N-terminus and binds both calcium and zinc ions. S100A7 is up-regulated in keratinocytes of psoriasis and atopic dermatitis lesions, as well as in epithelial cells of the tongue, eye, and female genital tract. Its up-regulation can be induced by bacterial exposure, inflammatory cytokines, or epidermal barrier disruption. S100A7 supports epithelial integrity through killing E. coli by sequestration of zinc and through inducing the up-regulation of tight junction proteins. The interaction of S100A7 with RAGE promotes the migration of immune cells and the infiltration of macrophages into tumor sites.
Purity Greater than 95% as determined by reducing SDS-PAGE.
Product Form Lyophilized
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Entotoxin Levels Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Reconstitution Dissolve the lyophilized protein in distilled water.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping The product is shipped at ambient temperature.
Datasheet

Material Safety Data Sheet
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