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BAN1905

BAN1905
  • Gene/Protein: P12277
  • Product Description: Creatine Kinase BB/CKB/B-CK
135.0000
Price in reward points: 135

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Creatine Kinase BB/CKB/B-CK
Protein Specification
Description Recombinant Human Creatine kinase B-type is produced by our E.coli expression system and the target gene encoding Met1-Lys381 is expressed with a 6His tag at the N-terminus.
Alternate Names B-CK; CKB; Creatine Kinase BB
Accession No. P12277
Amino Acid Range Met1-Lys381
Tag N-6His
Species Human
Source E.coli
Background Creatine kinase B-type (CKB) belongs to the ATP:guanido phosphotransferase family. It has dimer of identical or non-identical chains with MM being the major form in skeletal muscle and myocardium. MB exists in myocardium, and BB exists in many tissues, especially brain. CKB reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Clinically, creatine kinase is assayed in blood tests as a marker of myocardial infarction (heart attack), rhabdomyolysis (severe muscle breakdown), muscular dystrophy, autoimmune myositides and acute renal failure.
Purity Greater than 90% as determined by reducing SDS-PAGE.
Product Form Liquid
Formulation Supplied as a 0.2 μm filtered solution of 20mM TrisHCl,150mM NaCl,10% Glycerol,pH7.5.
Entotoxin Levels Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Storage Store at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles.
Shipping The product is shipped on dry ice/ice packs.
Datasheet

Material Safety Data Sheet
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