menu
Your Cart

ITA0103

ITA0103-3
ITA0103-2
ITA0103-1
ITA0103-4
ITA0103-3
ITA0103-2
ITA0103-1
ITA0103-4
ITA0103
  • Gene/Protein: MCM3AP
  • Product Description: Immunotag™ GANP Antibody
280.0000
Price in reward points: 280

Available Options

Immunotag™ GANP Antibody
Antibody Specification
Datasheet

Target Protein GANP
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC,IF/ICC,ELISA
Recommended Dilution WB: 1:500~1:3000 IHC: 1:50~1:200, IF/ICC 1:100-1:500
Concentration 1 mg/ml
Reactive Species Human,Mouse
Host Species Rabbit
Immunogen A synthesized peptide derived from human GANP
Specificity GANP antibody detects endogenous levels of total GANP
Purification The antiserum was purified by peptide affinity chromatography.
Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
Gene Name MCM3AP
Accession No. O60318
Alternate Names 80 kDa MCM3 associated protein; 80 kDa MCM3-associated protein; FLJ44336; FLJ45306; Germinal center associated nuclear protein; KIAA0572; MAP80; MCM3 import protein; MCM3 minichromosome maintenance deficient 3 associated protein; MCM3A; MCM3A_HUMAN; Mcm3ap; Minichromosome maintenance complex component 3 associated protein; Minichromosome maintenance deficient 3 associated protein; Minichromosome maintenance protein 3 associated protein; Protein GANP; SAC3;
Description Isoform GANP: Essential for the generation of high-affinity B-cells against T-cell-dependent antigens by affecting somatic hypermutation at the IgV-regions. May have stimulation-dependent DNA primase activity that would generate extra RNA primers in very rapidely proliferating cells and would support clonal expansion of differentiating B-cells (By similarity). Involved in the nuclear export of poly(A)-containing mRNAs by acting as a scaffold for the TREX-2 complex. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
Cell Pathway/ Category Primary Polyclonal Antibody
Protein MW 218kDa
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
English_US
Danish
Dutch
English_UK
French
German
Spanish
Norwegian
Portuguese
Finnish
Swedish
Polish

Write a review

Note: HTML is not translated!
Bad Good
Captcha

CONNECT WITH US