ITN0719
ITN0719
- Catalog: ITN0719
- Gene/Protein: FYCO1 ZFYVE7
- Product Description: Immunotag™ FYCO1 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | FYCO1 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from part region of human protein |
Specificity | FYCO1 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | FYCO1 ZFYVE7 |
Accession No. | Q9BQS8 Q8VDC1 |
Description | FYVE and coiled-coil domain containing 1(FYCO1) Homo sapiens This gene encodes a protein that contains a RUN domain, FYVE-type zinc finger domain and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P) and the autophagosome marker LC3. Mutations in this gene are a cause of autosomal recessive congenital cataract-2 (CATC2). [provided by RefSeq, Dec 2011], |
Protein Expression | Heart,Lung,Ovary,Skeletal muscle,Skin,Spleen, |
Subcellular Localization | lysosome,late endosome,autophagosome,membrane,integral component of membrane,cytoplasmic vesicle,intracellular membrane-bounded organelle, |
Protein Function | PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 FYVE-type zinc finger.,similarity:Contains 1 GOLD domain.,similarity:Contains 1 RUN domain.,tissue specificity:Expressed in heart and skeletal muscle., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |