ITN3031
ITN3031
- Catalog: ITN3031
- Gene/Protein: MAP1LC3C
- Product Description: Immunotag™ MLP3C Polyclonal Antibody
368.0000
Price in reward points: 368
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Antibody Specification | |
Datasheet | ![]() |
Target Protein | MLP3C |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from part region of human protein |
Specificity | MLP3C Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | MAP1LC3C |
Accession No. | Q9BXW4 |
Description | microtubule associated protein 1 light chain 3 gamma(MAP1LC3C) Homo sapiens Autophagy is a highly regulated bulk degradation process that plays an important role in cellular maintenance and development. MAP1LC3C is an ortholog of the yeast autophagosome protein Atg8 (He et al., 2003 [PubMed 12740394]).[supplied by OMIM, Nov 2010], |
Subcellular Localization | autophagosome membrane,autophagosome,cytosol,microtubule,endomembrane system,organelle membrane,cytoplasmic vesicle, |
Protein Function | function:Probably involved in formation of autophagosomal vacuoles (autophagosomes).,PTM:The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II.,similarity:Belongs to the MAP1 LC3 family.,subcellular location:LC3-II binds to the autophagic membranes.,subunit:3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins.,tissue specificity:Most abundant in placenta, lung and ovary., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |