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ITT5970

ITT5970
ITT5970
ITT5970
  • Catalog: ITT5970
  • Gene/Protein: CXCL3 GRO3 GROG SCYB3
  • Product Description: Immunotag™ GROγ Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ GROγ Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein GROγ
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application IHC-p,ELISA
Recommended Dilution IHC-p 1:50-200, ELISA 1:10000-20000
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen The antiserum was produced against synthesized peptide derived from the C-terminal region of human CXCL3. AA range:58-107
Specificity The antibody detects endogenous GROγ
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name CXCL3 GRO3 GROG SCYB3
Accession No. P19876 Q6W5C0
Alternate Names C-X-C motif chemokine 3 (GRO-gamma(1-73)) (Growth-regulated protein gamma) (GRO-gamma) (Macrophage inflammatory protein 2-beta) (MIP2-beta) [Cleaved into: GRO-gamma(5-73)]
Description C-X-C motif chemokine ligand 3(CXCL3) Homo sapiens This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. [provided by RefSeq, Sep 2014],
Cell Pathway/ Category Cytokine-cytokine receptor interaction,Chemokine,
Protein Expression Histiocytic lymphoma,Lung,Peripheral blood monocyte,Placenta,
Subcellular Localization extracellular region,extracellular space,
Protein Function function:Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes.,online information:CXCL3 entry,PTM:N-terminal processed form GRO-gamma(5-73) is produced by proteolytic cleavage after secretion from peripheral blood monocytes.,similarity:Belongs to the intercrine alpha (chemokine CxC) family.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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