ITT5970
ITT5970
- Catalog: ITT5970
- Gene/Protein: CXCL3 GRO3 GROG SCYB3
- Product Description: Immunotag™ GROγ Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | GROγ |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | IHC-p,ELISA |
Recommended Dilution | IHC-p 1:50-200, ELISA 1:10000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from the C-terminal region of human CXCL3. AA range:58-107 |
Specificity | The antibody detects endogenous GROγ |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | CXCL3 GRO3 GROG SCYB3 |
Accession No. | P19876 Q6W5C0 |
Alternate Names | C-X-C motif chemokine 3 (GRO-gamma(1-73)) (Growth-regulated protein gamma) (GRO-gamma) (Macrophage inflammatory protein 2-beta) (MIP2-beta) [Cleaved into: GRO-gamma(5-73)] |
Description | C-X-C motif chemokine ligand 3(CXCL3) Homo sapiens This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. [provided by RefSeq, Sep 2014], |
Cell Pathway/ Category | Cytokine-cytokine receptor interaction,Chemokine, |
Protein Expression | Histiocytic lymphoma,Lung,Peripheral blood monocyte,Placenta, |
Subcellular Localization | extracellular region,extracellular space, |
Protein Function | function:Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes.,online information:CXCL3 entry,PTM:N-terminal processed form GRO-gamma(5-73) is produced by proteolytic cleavage after secretion from peripheral blood monocytes.,similarity:Belongs to the intercrine alpha (chemokine CxC) family., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |