Datasheet |
|
Target Protein |
CLUS |
Clonality |
Polyclonal |
Storage/Stability |
-20°C/1 year |
Application |
WB,ELISA |
Recommended Dilution |
WB 1:500-2000, ELISA 1:10000-20000 |
Concentration |
1 mg/ml |
Reactive Species |
Human,Mouse,Rat |
Host Species |
Rabbit |
Immunogen |
Synthesized peptide derived from human CLUS Polyclonal |
Specificity |
This antibody detects endogenous levels of CLUS. |
Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form |
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name |
CLU APOJ CLI KUB1 AAG4 |
Accession No. |
P10909 Q06890 P05371 |
Alternate Names |
Clusterin (Aging-associated gene 4 protein) (Apolipoprotein J) (Apo-J) (Complement cytolysis inhibitor) (CLI) (Complement-associated protein SP-40,40) (Ku70-binding protein 1) (NA1/NA2) (Testosterone-repressed prostate message 2) (TRPM-2) [Cleaved into: Clusterin beta chain (ApoJalpha) (Complement cytolysis inhibitor a chain); Clusterin alpha chain (ApoJbeta) (Complement cytolysis inhibitor b chain)] |
Description |
clusterin(CLU) Homo sapiens The protein encoded by this gene is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Alternate splicing results in both coding and non-coding variants.[provided by RefSeq, May 2011], |
Protein Expression |
Astrocytoma,Brain,Fetal liver,Liver,Milk,Plasma,Platelet,Saliva,Small intestine,Testis, |
Subcellular Localization |
extracellular region,extracellular space,intracellular,nucleus,cytoplasm,mitochondrion,endoplasmic reticulum,Golgi apparatus,cytosol,cell surface,extracellular matrix,platelet alpha granule lumen,mitochondrial membrane,sph |
Protein Function |
function:Not yet clear. It is known to be expressed in a variety of tissues and it seems to be able to bind to cells, membranes and hydrophobic proteins. It has been associated with programmed cell death (apoptosis).,similarity:Belongs to the clusterin family.,subunit:Antiparallel disulfide-linked heterodimer. Interacts with APOA1, CLUAP1 AND PON1., |
Usage |
For Research Use Only! Not for diagnostic or therapeutic procedures. |