Cytokeratin 18 Antibody IHC
This antibody is intended for in vitro diagnostic (IVD) use.
The cytokeratin 18 (IHC018) antibody is intended for qualified laboratories to qualitatively identify by light microscopy the presence of associated antigens in sections of formalin-fixed, paraffin-embedded tissue sections using IHC test methods. Use of this antibody is indicated, subsequent to clinical differential diagnoses of diseases, as an aid in the identification of epithelia within the context of antibody panels, the patient’s clinical history and other diagnostic tests evaluated by a qualified pathologist.
Cytokeratin 18 usually multimerizes with cytokeratin 8 and is present in simple, glandular and transitional epithelial cells, but absent in stratified epithelial cells. Cytokeratin 18 stains adenocarcinomas of simple and glandular epithelium origin and poorly differentiated squamous carcinoma cells.