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Staurosporine


Staurosporine is a strong inhibitor of phosphalipid/Ca2+ dependent protein kinase and platelet aggregation. It is most commonly used as an inducer of apoptosis in several mammalian cell types. It is also used to study role of protein kinases in signal transduction as it inhibits other protein kinases such as cAMP- and cGMP-dependent protein kinase.

 

Specifications:

  • Source: Streptomyces sp.
  • Molecular Formula: C28H26N4O3
  • Molecular weight: 466.53
  • Purity: free base, >99% 
  • Cas Number: 62996-74-1
  • Form: Lyophilized powder

 

Application(s)

  • Staurosporine is used most commonly as inducer of apoptosis.
  • It inhibits several protein kinases such as phosphalipid/Ca2+ dependent protein kinase, cAMP- and cGMP-dependent protein kinase and thus used in signal transduction studies

 

Protocol
786-1545
786-1546
Material Safety Data Sheet
786-1545
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786-1546
English_US
Danish
Dutch
English_UK
French
German
Spanish
Norwegian
Portuguese
Finnish
Swedish
Polish

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