The bis-glucose compounds have a tetradhedral chiral carbon with two polar headgroups (the glucose moieties) and a long hydrophobic fluorinated tail. In this way they resemble the neo-pentyl glycol detergents, such as LMNG that have seen some recent success in structural biology.
Specifications
- Compound Name: ODG
- IUPAC Name: N-(2-methyl-1,3-bis(O-β-D-Glucose)propan-2-yl)-3-(octylthio)propanamide
- Application: Membrane Protein Extraction
- Surfactant type: Hydrogenated surfactant with a bis-glucose head group
- Molecular Formula: C27H51NO13S
- Molecular Weight: 629.8 g/mol
- Percent Composition: C (51.49%), H (8.16%), N (2.22%), O (33.03%), S (5.09%)
- Purity (HPLC, 214nm): ≤95%
- Retention time (RP18 HPLC): tR = 12.9 min
- Physical State: White powder
- Stability: Store in <-20°C freezer for up to one year
- Solubility: Soluble in water (0.5M), methanol and DMSO
- Critical Micelle Concentration: >10 mM