Oxidative Modification Kit is designed for the modification of glycoproteins to reactive aldehydes for amine- and hydrazide- labeling. Sodium metaperiodate, or sodium m-periodate, is a mild oxidant that is routinely used for the conversion of cis-glycol groups in carbohydrates to reactive aldehdye groups.
Carbohydrate groups present in some glycoproteins are preferred site for modification or cross linking as they allow for modification away from amino acids in polypeptide that are important for protein activity.
Features
- modify carbohydrate cis-glycol group of glycoproteins to reactive aldehydes.
- Suitable for amine- and hydrazide- labeling.
Application(s)
- modify carbohydrate cis-glycol group of glycoproteins to reactive aldehydes for amine-and hydrazide labeling
