Cytokeratin Cocktail Antibody IHC
This antibody is intended for in vitro diagnostic (IVD) use.
The Cytokeratin Cocktail (IHC559) antibody is intended for qualified laboratories to qualitatively identify by light microscopy the presence of associated antigens in sections of formalin-fixed, paraffin-embedded tissue sections using IHC test methods. Use of this antibody is indicated, subsequent to clinical differential diagnoses of diseases, as an aid in the identification of tumors of epithelial origin within the context of antibody panels, the patient’s clinical history and other diagnostic tests evaluated by a qualified pathologist.
Cytokeratin Cocktail is a combination of type I cytokeratins (10, 14, 15, 16, & 19) and type II cytokeratins (1, 2, 3, 4, 5, 6, 7, & 8). The cocktail stains most carcinomas of different organ origin, but usually does not stain chromophobe renal cell carcinoma, hepatocellular carcinoma, some clear cell renal cell carcinomas, adrenal corticol carcinoma, and renal oncocytoma. The cocktail may also react with other intermediate filaments, including glial fibrillary acidic protein, and produce false-positive results in glial cancers.