Protein Cross-linking (1 Citations)
A single protein molecule rarely carries out its role in the body on its own. Many proteins and cofactors are often involved and act as regulators, activators or inhibitors of the protein’s function. Researchers are constantly on the hunt for biomolecules that interact with their protein of interest and routinely use specialized molecules known as cross-linkers.
Cross-linkers are small chemical bridges that interact with specific regions of a protein and as a result are able to covalently link proteins that are interacting due to their close proximity to each other.
This kit allows students to use a protein crosslinker to chemically link proteins together and subsequently visualize the linked proteins. This kit uses a reversible cross linker, so students can visualize coupling and release of cross linked proteins.
Supplied with components needed for hands-on experimentation for six workstations of 4-5 students or 24-30 students. Supplied with Teacher’s Guide and separate Student’s Guides.
Simple, easily visualized cross-linking experiment
Introduction to protein cross-linking
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