| Catalog | Description | Size | Price (USD) | Qty |
|---|---|---|---|---|
| GBM-1277-100MG | 5-Fluorouridine | 100mg | $126.00 | |
| GBM-1277-250MG | 5-Fluorouridine | 250mg | $273.00 |
| Bioassays Specification | |
| Bio-Activity | Proapoptotic antiproliferative agent |
| Chemical Name | 1-(β-D-Ribofuranosyl)-5-fluorouracil |
| Function / Pharmacology | Inhibitor of ribozyme self-cleavage in mammalian cells.1 Induces apoptosis in HCT-116 colorectal carcinoma cells causing diverse gene expression patterns suggesting that mechanisms besides global inhibition of RNA synthesis and processing contribute to 5-fluorouridine cytotoxicity.2 Cell permeable and active in vivo. |
| CAS# | 316-46-1 |
| MW | 262.19 |
| Molecular Formula | C9H11FN2O6 |
| Solubility | Soluble in DMSO (up to 50 mg/ml) in Water (up to 50 mg/ml) or in Ethanol (up to 6 mg/ml with warming) |
| Supplied | powder |
| Storage as supplied | -20°C |
| Ship temp | Ambient |
| References | 1) Yen et al. (2006), Identification of inhibitors of ribozyme self-cleavage in mammalian cells via high-throughput screening of chemical libraries; RNA, 12 797 2) Schmittgen et al. (2005), Diverse gene expression pattern during 5-fluorouridine-induced apoptosis; Int. J. Oncol., 27 297 |
| Antibody Specification | |
| Alternate Names | FUrd |
| Protein Specification | |
| Purity | >98% |
| Bioassays Specification | |
| Bio-Activity | Proapoptotic antiproliferative agent |
| Chemical Name | 1-(β-D-Ribofuranosyl)-5-fluorouracil |
| Function / Pharmacology | Inhibitor of ribozyme self-cleavage in mammalian cells.1 Induces apoptosis in HCT-116 colorectal carcinoma cells causing diverse gene expression patterns suggesting that mechanisms besides global inhibition of RNA synthesis and processing contribute to 5-fluorouridine cytotoxicity.2 Cell permeable and active in vivo. |
| CAS# | 316-46-1 |
| MW | 262.19 |
| Molecular Formula | C9H11FN2O6 |
| Solubility | Soluble in DMSO (up to 50 mg/ml) in Water (up to 50 mg/ml) or in Ethanol (up to 6 mg/ml with warming) |
| Supplied | powder |
| Storage as supplied | -20°C |
| Ship temp | Ambient |
| References | 1) Yen et al. (2006), Identification of inhibitors of ribozyme self-cleavage in mammalian cells via high-throughput screening of chemical libraries; RNA, 12 797 2) Schmittgen et al. (2005), Diverse gene expression pattern during 5-fluorouridine-induced apoptosis; Int. J. Oncol., 27 297 |
| Antibody Specification | |
| Alternate Names | FUrd |
| Protein Specification | |
| Purity | >98% |
