A selection of strong chemicals to aid in the denaturation of proteins. Denaturants, or chaotropes, disrupt water interactions resulting in the solubilization of hydrophobic proteins and peptides. The chaotropes also act on all proteins to unfold them and alter their three-dimensional structure.
Available as a powder or 8M solution
- Synonym: Aminoformamidine hydrochloride, Aminomethanamidine hydrochloride, Guanidinium chloride
- CAS Number: 50-01-1
- Linear Formula: NH2C(=NH)NH2 · HCl
- Molecular Weight: 95.53