ITA3757
ITA3757
- Catalog: ITA3757
- Gene/Protein: MAS1
- Product Description: Immunotag™ MAS Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
|
| Target Protein | MAS |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-1:2000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide |
| Specificity | MAS antibody detects endogenous levels of total MAS |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Gene Name | MAS1 |
| Accession No. | P04201 |
| Alternate Names | MAS; MAS proto oncogene; Mas-related G protein-coupled receptor A; MAS_HUMAN; Mas1; MAS1 oncogene; MAS1 proto-oncogene, G protein-coupled receptor; MGRA; Proto-oncogene Mas; |
| Description | Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 37 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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