ITA4267
ITA4267
- Catalog: ITA4267
- Gene/Protein: EZH1
- Product Description: Immunotag™ EZH1 Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | EZH1 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC,IF/ICC,ELISA |
Recommended Dilution | WB 1:500~1:1000 IHC: 1:50~1:200, IF/ICC 1:100-1:500 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | A synthesized peptide |
Specificity | EZH1 Antibody detects endogenous levels of total EZH1 |
Purification | The antiserum was purified by peptide affinity chromatography. |
Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
Gene Name | EZH1 |
Accession No. | Q92800 |
Alternate Names | Enhancer of zeste homolog 1 (Drosophila); Enhancer of zeste homolog 1; ENX-2; ENX2; Ezh1; EZH1_HUMAN; Histone-lysine N-methyltransferase EZH1; |
Description | Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. |
Cell Pathway/ Category | Primary Polyclonal Antibody |
Protein MW | 85 KD |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |