ITA4399
ITA4399
- Catalog: ITA4399
- Gene/Protein: ARRDC3
- Product Description: Immunotag™ ARRDC3 Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | ARRDC3 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IF/ICC,ELISA |
Recommended Dilution | WB 1:500~1:1000, IF/ICC 1:100-1:500 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | A synthesized peptide |
Specificity | ARRDC3 Antibody detects endogenous levels of total ARRDC3 |
Purification | The antiserum was purified by peptide affinity chromatography. |
Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
Gene Name | ARRDC3 |
Accession No. | Q96B67 |
Alternate Names | ARRDC 3; Arrestin domain containing 3; Arrestin domain containing protein 3; KIAA1376; TBP-2-like inducible membrane protein; Thioredoxin binding protein 2 like inducible membrane; TLIMP; |
Description | Adapter protein that plays a role in regulating cell-surface expression of adrenergic receptors and probably also other G protein-coupled receptors (PubMed:20559325, PubMed:21982743, PubMed:23208550). Plays a role in NEDD4-mediated ubiquitination and endocytosis af activated ADRB2 and subsequent ADRB2 degradation (PubMed:20559325, PubMed:23208550). May recruit NEDD4 to ADRB2 (PubMed:20559325). Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes (PubMed:23208550). |
Cell Pathway/ Category | Primary Polyclonal Antibody |
Protein MW | 46 KD |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |