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ITA7338

ITA7338-1
ITA7338-2
ITA7338-3
ITA7338-1
ITA7338-2
ITA7338-3
ITA7338
  • Catalog: ITA7338
  • Gene/Protein: PTGES3
  • Product Description: Immunotag™ PTGES3 Antibody
385.0000
Price in reward points: 385

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Immunotag™ PTGES3 Antibody
Antibody Specification
Datasheet

Target Protein PTGES3
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC,IF/ICC,ELISA
Recommended Dilution WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen A synthesized peptide derived from human PTGES3
Specificity PTGES3 Antibody detects endogenous levels of total PTGES3
Purification The antiserum was purified by peptide affinity chromatography.
Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
Gene Name PTGES3
Accession No. Q15185
Alternate Names Co chaperone p23; cPGES; Cytosolic prostaglandin E synthase; Cytosolic prostaglandin E2 synthase; Hsp90 co chaperone; Hsp90 co-chaperone; P23; Progesterone receptor complex; Progesterone receptor complex p23; Prostaglandin E synthase 3 (cytosolic); Prostaglandin E synthase 3; PTGES 3; PTGES3; Sid 3177; TEBP; TEBP_HUMAN; Telomerase binding protein p23; Telomerase-binding protein p23; Unactive progesterone receptor 23 kD;
Description Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) (PubMed:10922363). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes (PubMed:11274138, PubMed:12077419). Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway (PubMed:24711448).
Cell Pathway/ Category Primary Polyclonal Antibody
Protein MW 19kDa
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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