ITA7448
ITA7448
- Catalog: ITA7448
- Gene/Protein: PRDM14
- Product Description: Immunotag™ PRDM14 Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
|
| Target Protein | PRDM14 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC,IF/ICC,IP,ELISA,CHIP |
| Recommended Dilution | WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200 IP 1:20-1:100 CHIP 1:20-1:100 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human PRDM14 |
| Specificity | PRDM14 Antibody detects endogenous levels of total PRDM14 |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | PRDM14 |
| Accession No. | Q9GZV8 |
| Alternate Names | MGC59730; PFM 11; PFM11; PR domain containing 14; PR domain zinc finger protein 14; PR domain-containing protein 14; PRD14_HUMAN; PRDM 14; PRDM14; |
| Description | Transcription factor that has both positive and negative roles on transcription. Required for the maintenance of emryonic stem cell identity and the reacquisition of pluripotency in somatic cells. May play an essential role in germ cell development at 2 levels: the reacquisition of potential pluripotency, including SOX2 up-regulation, and successful epigenetic reprogramming, characterized by EHMT1 repression. Its association with CBFA2T2 is required for the functions in pluripotency and germ cell formation (By similarity). Directly up-regulates the expression of pluripotency gene POU5F1 through its proximal enhancer. Binds to the DNA consensus sequence 5'-GGTC[TC]CTAA-3'. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 64kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
| English_US |
|
| Danish |
|
| Dutch |
|
| English_UK |
|
| French |
|
| German |
|
| Spanish |
|
| Norwegian |
|
| Portuguese |
|
| Finnish |
|
| Swedish |
|
| Polish |
|