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ITA8335

ITA8335-2
ITA8335-1
ITA8335-2
ITA8335-1
ITA8335
  • Gene/Protein: PPP2CA
  • Product Description: Immunotag™ PP2A-C alpha/β Antibody
280.0000
Price in reward points: 280

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Immunotag™ PP2A-C alpha/β Antibody
Antibody Specification
Datasheet

Target Protein PP2A-C alpha/β
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IF/ICC,ELISA
Recommended Dilution WB 1:1000-3000, IF/ICC 1:100-1:500
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen A synthesized peptide derived from human PP2A-C alpha/β
Specificity PP2A-C alpha/β Antibody detects endogenous levels of total PP2A-C alpha/β
Purification The antiserum was purified by peptide affinity chromatography.
Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
Gene Name PPP2CA
Accession No. P67775/P62714
Alternate Names PP2A alpha; PP2A-alpha; PP2AA_HUMAN; PP2Aalpha; PP2Ac; PP2CA; PP2Calpha; PPP2CA; Protein phosphatase 2 (formerly 2A) catalytic subunit alpha isoform; Protein phosphatase 2 catalytic subunit alpha isoform; Protein phosphatase 2, catalytic subunit, alpha isozyme; Protein phosphatase 2A catalytic subunit, alpha isoform; Replication protein C; RP C; RP-C; RPC; Serine/threonine protein phosphatase 2A catalytic subunit alpha isoform; Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A A; PP2A alpha; PP2A B; PP2A beta; PP2A-alpha; PP2AA_HUMAN; PP2Ac; PP2CB; PPP2CA; PPP2CB; Protein phosphatase 2 catalytic subunit alpha isoform; Protein phosphatase 2 catalytic subunit beta isoform; Replication protein C; RP C; RP-C; Serine/threonine protein phosphatase 2A catalytic subunit alpha isoform; Serine/threonine protein phosphatase 2A catalytic subunit beta isoform; Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform;
Description PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.
Cell Pathway/ Category Primary Polyclonal Antibody
Protein MW 35 kDa
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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