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ITA8526

ITA8526-1
ITA8526-2
ITA8526-1
ITA8526-2
ITA8526
  • Catalog: ITA8526
  • Gene/Protein: NR2C1
  • Product Description: Immunotag™ NR2C1 Antibody
385.0000
Price in reward points: 385

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Immunotag™ NR2C1 Antibody
Antibody Specification
Datasheet

Target Protein NR2C1
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC,ELISA
Recommended Dilution WB 1:1000-3000 IHC 1:200
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen A synthesized peptide derived from human NR2C1
Specificity NR2C1 Antibody detects endogenous levels of total NR2C1
Purification The antiserum was purified by peptide affinity chromatography.
Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
Gene Name NR2C1
Accession No. P13056
Alternate Names NR2C 1; NR2C1; NR2C1_HUMAN; NUCLEAR HORMONE RECEPTOR TR2; Nuclear receptor subfamily 2 Group C isoform; Nuclear receptor subfamily 2 group C member 1; Orphan nuclear receptor TR2; Testicular receptor 2; TR 2; TR2;
Description Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Also activator of OCT4 gene expression. May be involved in stem cell proliferation and differentiation. Mediator of retinoic acid-regulated preadipocyte proliferation.
Cell Pathway/ Category Primary Polyclonal Antibody
Protein MW 67 kDa
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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