ITA8526
ITA8526
- Catalog: ITA8526
- Gene/Protein: NR2C1
- Product Description: Immunotag™ NR2C1 Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | NR2C1 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC,ELISA |
Recommended Dilution | WB 1:1000-3000 IHC 1:200 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | A synthesized peptide derived from human NR2C1 |
Specificity | NR2C1 Antibody detects endogenous levels of total NR2C1 |
Purification | The antiserum was purified by peptide affinity chromatography. |
Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
Gene Name | NR2C1 |
Accession No. | P13056 |
Alternate Names | NR2C 1; NR2C1; NR2C1_HUMAN; NUCLEAR HORMONE RECEPTOR TR2; Nuclear receptor subfamily 2 Group C isoform; Nuclear receptor subfamily 2 group C member 1; Orphan nuclear receptor TR2; Testicular receptor 2; TR 2; TR2; |
Description | Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Also activator of OCT4 gene expression. May be involved in stem cell proliferation and differentiation. Mediator of retinoic acid-regulated preadipocyte proliferation. |
Cell Pathway/ Category | Primary Polyclonal Antibody |
Protein MW | 67 kDa |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |