ITA9244
ITA9244
- Catalog: ITA9244
- Gene/Protein: EDEM2
- Product Description: Immunotag™ EDEM2 Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | EDEM2 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:1000-3000 |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | A synthesized peptide derived from human EDEM2 |
Specificity | EDEM2 Antibody detects endogenous levels of total EDEM2 |
Purification | The antiserum was purified by peptide affinity chromatography. |
Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
Gene Name | EDEM2 |
Accession No. | Q9BV94 |
Alternate Names | bA4204.1; C20orf31; C20orf49; EDEM 2; EDEM2; EDEM2_HUMAN; ER degradation enhancer mannosidase alpha like 2; ER degradation enhancing alpha mannosidase like 2; ER degradation enhancing alpha mannosidase like protein 2; ER degradation enhancing mannosidase like protein 2; ER degradation-enhancing alpha-mannosidase-like 2; FLJ10783; UNQ573/PRO1135; |
Description | Initiates the endoplasmic reticulum-associated degradation (ERAD) that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. Catalyzes the first mannose trimming step, from Man9GlcNAc2 to Man8GlcNAc2 (PubMed:25092655). Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. |
Cell Pathway/ Category | Primary Polyclonal Antibody |
Protein MW | 65 kDa |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |