ITC0086
ITC0086
- Catalog: ITC0086
- Gene/Protein: GGT7
- Product Description: Immunotag™ Cleaved-GGT4 HC (T472) Polyclonal Antibody
460.0000
Price in reward points: 460
| Antibody Specification | |
| Datasheet | 
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| Target Protein | GGT4 HC (T472) |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from Cleaved-GGT4 HC (T472), at AA range: 400-480 |
| Specificity | Cleaved-GGT4 HC (T472) Polyclonal Antibody detects endogenous levels of fragment of activated GGT4 HC protein resulting from cleavage adjacent to T472. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | GGT7 |
| Accession No. | Q9UJ14 Q99JP7 Q99MZ4 |
| Alternate Names | GGT7; GGTL3; GGTL5; Gamma-glutamyltransferase 7; GGT 7; Gamma-glutamyltransferase-like 3; Gamma-glutamyltransferase-like 5; Gamma-glutamyltranspeptidase 7; Glutathione hydrolase 7 |
| Description | gamma-glutamyltransferase 7(GGT7) Homo sapiens This gene is a member of a gene family that encodes enzymes involved in both the metabolism of glutathione and in the transpeptidation of amino acids. Changes in the activity of gamma-glutamyltransferase may signal preneoplastic or toxic conditions in the liver or kidney. The protein encoded by this gene consists of a heavy and a light chain, and it can interact with CT120, a plasma membrane-associated protein that is possibly involved in lung carcinogenesis. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Taurine and hypotaurine metabolism,Selenoamino acid metabolism,Cyanoamino acid metabolism,Glutathione metabolism,Arachidonic acid metabolism, |
| Protein Expression | Brain,Spleen, |
| Subcellular Localization | integral component of membrane,anchored component of external side of plasma membrane, |
| Protein Function | catalytic activity:(5-L-glutamyl)-peptide + an amino acid = peptide + 5-L-glutamyl amino acid.,function:Cleaves glutathione conjugates.,pathway:Sulfur metabolism; glutathione metabolism.,similarity:Belongs to the gamma-glutamyltransferase family.,subunit:Heterodimer composed of the light and heavy chains. The active site is located in the light chain (By similarity). Isoform 3 interacts with FAM57A.,tissue specificity:Widely expressed, but at low level, except in the airway epithelial cells. Detected in brain, heart, kidney, liver, lung, spleen, testis and trachea., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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