ITM0006
ITM0006
- Catalog: ITM0006
- Gene/Protein: GOT2
- Product Description: Immunotag™ AATM Monoclonal Antibody
504.0000
Price in reward points: 504
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Antibody Specification | |
Datasheet | |
Target Protein | AATM |
Clonality | Monoclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IF,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat,Monkey |
Host Species | Mouse |
Immunogen | Purified recombinant fragment of human AATM expressed in E Coli |
Specificity | AATM Monoclonal Antibody detects endogenous levels of AATM protein. |
Purification | Affinity purification |
Form | Ascitic fluid containing 0.03% sodium azide. |
Gene Name | GOT2 |
Accession No. | P00505 P05202 P00507 |
Alternate Names | GOT2; Aspartate aminotransferase; mitochondrial; mAspAT; Fatty acid-binding protein; FABP-1; Glutamate oxaloacetate transaminase 2; Kynurenine aminotransferase 4; Kynurenine aminotransferase IV; Kynurenine--oxoglutarate transaminase 4; Kynu |
Description | glutamic-oxaloacetic transaminase 2(GOT2) Homo sapiens Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013], |
Cell Pathway/ Category | Alanine, aspartate and glutamate metabolism,Cysteine and methionine metabolism,Arginine and proline metabolism,Tyrosine metabolism,Phenylalanine metabolism,Phenylalanine, tyrosine and tryptophan biosynthesis, |
Protein Expression | Epithelium,Gastric mucosa,Muscle, |
Subcellular Localization | mitochondrion,mitochondrial inner membrane,mitochondrial matrix,plasma membrane,cell surface,perikaryon,myelin sheath,protein complex,extracellular exosome, |
Protein Function | catalytic activity:L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.,cofactor:Pyridoxal phosphate.,function:Facilitates cellular uptake of long-chain free fatty acids.,miscellaneous:In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.,similarity:Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.,subunit:Homodimer., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |