ITM0059
ITM0059
- Catalog: ITM0059
- Gene/Protein: BDH1
- Product Description: Immunotag™ BDH1 Monoclonal Antibody
504.0000
Price in reward points: 504
| Antibody Specification | |
| Datasheet | 
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| Target Protein | BDH1 |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Mouse |
| Immunogen | Purified recombinant fragment of human BDH1 expressed in E. Coli. |
| Specificity | BDH1 Monoclonal Antibody detects endogenous levels of BDH1 protein. |
| Purification | Affinity purification |
| Form | Ascitic fluid containing 0.03% sodium azide. |
| Gene Name | BDH1 |
| Accession No. | Q02338 Q80XN0 |
| Alternate Names | BDH1; BDH; D-beta-hydroxybutyrate dehydrogenase; mitochondrial; BDH; 3-hydroxybutyrate dehydrogenase |
| Description | 3-hydroxybutyrate dehydrogenase, type 1(BDH1) Homo sapiens This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Synthesis and degradation of ketone bodies,Butanoate metabolism, |
| Protein Expression | Heart,Lung,Ovary, |
| Subcellular Localization | nucleoplasm,cytoplasm,mitochondrion,mitochondrial matrix,matrix side of mitochondrial inner membrane, |
| Protein Function | catalytic activity:(R)-3-hydroxybutanoate + NAD(+) = acetoacetate + NADH.,enzyme regulation:Requires phosphatidylcholine as an allosteric activator for enzymatic activity.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family.,subunit:Homotetramer., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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