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ITM0059

ITM0059
  • Gene/Protein: BDH1
  • Product Description: Immunotag™ BDH1 Monoclonal Antibody
368.0000
Price in reward points: 368

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Immunotag™ BDH1 Monoclonal Antibody
Antibody Specification
Datasheet
Target Protein BDH1
Clonality Monoclonal
Storage/Stability -20°C/1 year
Application WB,IHC-p,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human,Mouse
Host Species Mouse
Immunogen Purified recombinant fragment of human BDH1 expressed in E. Coli.
Specificity BDH1 Monoclonal Antibody detects endogenous levels of BDH1 protein.
Purification Affinity purification
Form Ascitic fluid containing 0.03% sodium azide.
Gene Name BDH1
Accession No. Q02338 Q80XN0
Alternate Names BDH1; BDH; D-beta-hydroxybutyrate dehydrogenase; mitochondrial; BDH; 3-hydroxybutyrate dehydrogenase
Description 3-hydroxybutyrate dehydrogenase, type 1(BDH1) Homo sapiens This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008],
Cell Pathway/ Category Synthesis and degradation of ketone bodies,Butanoate metabolism,
Protein Expression Heart,Lung,Ovary,
Subcellular Localization nucleoplasm,cytoplasm,mitochondrion,mitochondrial matrix,matrix side of mitochondrial inner membrane,
Protein Function catalytic activity:(R)-3-hydroxybutanoate + NAD(+) = acetoacetate + NADH.,enzyme regulation:Requires phosphatidylcholine as an allosteric activator for enzymatic activity.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family.,subunit:Homotetramer.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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