ITM0063
ITM0063
- Catalog: ITM0063
- Gene/Protein: PRDM1
- Product Description: Immunotag™ Blimp-1 Monoclonal Antibody
504.0000
Price in reward points: 504
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Blimp-1 |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Mouse |
| Immunogen | Purified recombinant fragment of human Blimp-1 expressed in E. Coli. |
| Specificity | Blimp-1 Monoclonal Antibody detects endogenous levels of Blimp-1 protein. |
| Purification | Affinity purification |
| Form | Ascitic fluid containing 0.03% sodium azide. |
| Gene Name | PRDM1 |
| Accession No. | O75626 Q60636 |
| Alternate Names | PRDM1; BLIMP1; PR domain zinc finger protein 1; BLIMP-1; Beta-interferon gene positive regulatory domain I-binding factor; PR domain-containing protein 1; Positive regulatory domain I-binding factor 1; PRDI-BF1; PRDI-binding factor 1 |
| Description | PR/SET domain 1(PRDM1) Homo sapiens This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported. [provided by RefSeq, Jul 2008], |
| Protein Expression | PCR rescued clones,Stomach, |
| Subcellular Localization | nucleus,nucleoplasm,cytoplasm, |
| Protein Function | function:Transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells.,similarity:Contains 1 SET domain.,similarity:Contains 4 C2H2-type zinc fingers.,subunit:Interacts with PRMT5., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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