ITM0139
ITM0139
- Catalog: ITM0139
- Gene/Protein: KLRD1
- Product Description: Immunotag™ CD94 Monoclonal Antibody
504.0000
Price in reward points: 504
| Antibody Specification | |
| Datasheet | 
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| Target Protein | CD94 |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Mouse |
| Immunogen | Purified recombinant fragment of human CD94 expressed in E. Coli. |
| Specificity | CD94 Monoclonal Antibody detects endogenous levels of CD94 protein. |
| Purification | Affinity purification |
| Form | Ascitic fluid containing 0.03% sodium azide. |
| Gene Name | KLRD1 |
| Accession No. | Q13241 O54707 |
| Alternate Names | KLRD1; CD94; Natural killer cells antigen CD94; KP43; Killer cell lectin-like receptor subfamily D member 1; NK cell receptor; CD antigen CD94 |
| Description | killer cell lectin like receptor D1(KLRD1) Homo sapiens Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Antigen processing and presentation,Natural killer cell mediated cytotoxicity,Graft-versus-host disease, |
| Protein Expression | Blood,Placenta, |
| Subcellular Localization | plasma membrane,external side of plasma membrane,integral component of membrane,receptor complex, |
| Protein Function | function:Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.,online information:CD94,similarity:Contains 1 C-type lectin domain.,subunit:Can form disulfide-bonded heterodimer with NKG2 family members.,tissue specificity:Natural killer cells., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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