ITM0432
ITM0432
- Catalog: ITM0432
- Gene/Protein: CSF1
- Product Description: Immunotag™ M-CSF Monoclonal Antibody
504.0000
Price in reward points: 504
| Antibody Specification | |
| Datasheet | 
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| Target Protein | M-CSF |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Mouse |
| Immunogen | Purified recombinant fragment of human M-CSF expressed in E. Coli. |
| Specificity | M-CSF Monoclonal Antibody detects endogenous levels of M-CSF protein. |
| Purification | Affinity purification |
| Form | Ascitic fluid containing 0.03% sodium azide. |
| Gene Name | CSF1 |
| Accession No. | P09603 P07141 |
| Alternate Names | CSF1; Macrophage colony-stimulating factor 1; CSF-1; M-CSF; MCSF; Lanimostim |
| Description | colony stimulating factor 1(CSF1) Homo sapiens The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011], |
| Cell Pathway/ Category | Cytokine-cytokine receptor interaction,Hematopoietic cell lineage, |
| Protein Expression | Endometrium,Kidney,Pancreatic carcinoma,T lymphoblast,Trophoblast,Urine, |
| Subcellular Localization | extracellular space,plasma membrane,membrane,integral component of membrane,perinuclear region of cytoplasm,extracellular exosome,CSF1-CSF1R complex, |
| Protein Function | function:Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy.,PTM:Glycosylation and proteolytic cleavage yield different soluble forms. A high molecular weight soluble form is a proteoglycan containing chondroitin sulfate.,PTM:Isoform 1 is N- and O-glycosylated. Isoform 3 is N-glycosylated.,subunit:Homodimer or heterodimer; disulfide-linked., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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