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ITM0521

ITM0521
  • Gene/Protein: RCHY1
  • Product Description: Immunotag™ Pirh2 Monoclonal Antibody
368.0000
Price in reward points: 368

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Immunotag™ Pirh2 Monoclonal Antibody
Antibody Specification
Datasheet
Target Protein Pirh2
Clonality Monoclonal
Storage/Stability -20°C/1 year
Application WB,IHC-p,IF,FCM,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human,Rat
Host Species Mouse
Immunogen Purified recombinant fragment of human Pirh2 expressed in E. Coli.
Specificity Pirh2 Monoclonal Antibody detects endogenous levels of Pirh2 protein.
Purification Affinity purification
Form Ascitic fluid containing 0.03% sodium azide.
Gene Name RCHY1
Accession No. Q96PM5 Q9CR50
Alternate Names RCHY1; ARNIP; CHIMP; PIRH2; RNF199; ZNF363; RING finger and CHY zinc finger domain-containing protein 1; Androgen receptor N-terminal-interacting protein; CH-rich-interacting match with PLAG1; E3 ubiquitin-protein ligase Pirh2; RING finger
Description ring finger and CHY zinc finger domain containing 1(RCHY1) Homo sapiens The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including tumor protein 53, histone deacetylase 1, and cyclin-dependent kinase inhibitor 1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2013],
Cell Pathway/ Category p53,Ubiquitin mediated proteolysis,
Protein Expression Liver,Platelet,Skin,Uterus,
Subcellular Localization ubiquitin ligase complex,nucleus,nucleoplasm,cytoplasm,nuclear speck,
Protein Function similarity:Contains 1 CHY-type zinc finger.,similarity:Contains 1 CTCHY-type zinc finger.,similarity:Contains 1 RING-type zinc finger.,subunit:Interacts with AR, PLAG1 and SCYL1BP1/NTKLBP1.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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