ITM0521
ITM0521
- Catalog: ITM0521
- Gene/Protein: RCHY1
- Product Description: Immunotag™ Pirh2 Monoclonal Antibody
504.0000
Price in reward points: 504
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Pirh2 |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,IF,FCM,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Rat |
| Host Species | Mouse |
| Immunogen | Purified recombinant fragment of human Pirh2 expressed in E. Coli. |
| Specificity | Pirh2 Monoclonal Antibody detects endogenous levels of Pirh2 protein. |
| Purification | Affinity purification |
| Form | Ascitic fluid containing 0.03% sodium azide. |
| Gene Name | RCHY1 |
| Accession No. | Q96PM5 Q9CR50 |
| Alternate Names | RCHY1; ARNIP; CHIMP; PIRH2; RNF199; ZNF363; RING finger and CHY zinc finger domain-containing protein 1; Androgen receptor N-terminal-interacting protein; CH-rich-interacting match with PLAG1; E3 ubiquitin-protein ligase Pirh2; RING finger |
| Description | ring finger and CHY zinc finger domain containing 1(RCHY1) Homo sapiens The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including tumor protein 53, histone deacetylase 1, and cyclin-dependent kinase inhibitor 1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2013], |
| Cell Pathway/ Category | p53,Ubiquitin mediated proteolysis, |
| Protein Expression | Liver,Platelet,Skin,Uterus, |
| Subcellular Localization | ubiquitin ligase complex,nucleus,nucleoplasm,cytoplasm,nuclear speck, |
| Protein Function | similarity:Contains 1 CHY-type zinc finger.,similarity:Contains 1 CTCHY-type zinc finger.,similarity:Contains 1 RING-type zinc finger.,subunit:Interacts with AR, PLAG1 and SCYL1BP1/NTKLBP1., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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