ITM0541
ITM0541
- Catalog: ITM0541
- Gene/Protein: PTH
- Product Description: Immunotag™ PTH Monoclonal Antibody
504.0000
Price in reward points: 504
| Antibody Specification | |
| Datasheet | 
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| Target Protein | PTH |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Mouse |
| Immunogen | Purified recombinant fragment of human PTH (aa1-115) expressed in E. Coli. |
| Specificity | PTH Monoclonal Antibody detects endogenous levels of PTH protein. |
| Purification | Affinity purification |
| Form | Ascitic fluid containing 0.03% sodium azide. |
| Gene Name | PTH |
| Accession No. | P01270 |
| Alternate Names | PTH; Parathyroid hormone; PTH; Parathormone; Parathyrin |
| Description | parathyroid hormone(PTH) Homo sapiens This gene encodes a member of the parathyroid family of proteins. The encoded preproprotein is proteolytically processed to generate a protein that binds to the parathyroid hormone/parathyroid hormone-related peptide receptor and regulates blood calcium and phosphate levels. Excess production of the encoded protein, known as hyperparathyroidism, can result in hypercalcemia and kidney stones. On the other hand, defective processing of the encoded protein may lead to hypoparathyroidism, which can result in hypocalcemia and numbness. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015], |
| Subcellular Localization | extracellular region,extracellular space,intracellular, |
| Protein Function | disease:Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH) [MIM:146200]. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.,function:PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion.,online information:Parathyroid hormone entry,similarity:Belongs to the parathyroid hormone family., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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