ITM1269
ITM1269
- Catalog: ITM1269
- Gene/Protein: ppp5c
- Product Description: Immunotag™ PP5 mouse mAb
405.0000
Price in reward points: 405
| Antibody Specification | |
| Datasheet | 
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| Target Protein | PP5 |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB |
| Recommended Dilution | wb 1:1000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Mouse |
| Immunogen | Purified recombinant human PP5 protein fragments expressed in E.coli. |
| Specificity | This antibody detects endogenous levels of PP5 and does not cross-react with related protein |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | ppp5c |
| Accession No. | P53041 Q60676 |
| Alternate Names | FLJ36922;FLJ55954;OTTHUMP00000165834;PP-T;PP5;PPP5;PPP5_HUMAN;PPP5C;PPT;Protein phosphatase 5, catalytic subunit;Protein phosphatase T;Serine/threonine protein phosphatase 5;Serine/threonine-protein phosphatase 5. |
| Description | protein phosphatase 5 catalytic subunit(PPP5C) Homo sapiens This gene encodes a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family. Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011], |
| Cell Pathway/ Category | MAPK_ERK_Growth,MAPK_G_Protein, |
| Protein Expression | Cervix,Fetal brain,Muscle,Spleen,Stomach mucosa, |
| Subcellular Localization | nucleus,nucleoplasm,cytoplasm,cytosol,plasma membrane,perikaryon,intracellular membrane-bounded organelle,protein complex,cell periphery,proximal dendrite, |
| Protein Function | catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,cofactor:Binds 1 iron ion per subunit.,cofactor:Binds 1 manganese ion per subunit.,function:May play a role in the regulation of RNA biogenesis and/or mitosis. In vitro, dephosphorylates serine residues of skeletal muscle phosphorylase and histone H1.,similarity:Belongs to the PPP phosphatase family.,similarity:Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.,similarity:Contains 3 TPR repeats.,subcellular location:Predominantly nuclear. But also present in the cytoplasm.,subunit:Interacts with CDC16 and CDC27.,tissue specificity:Ubiquitous., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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