ITM1319
ITM1319
- Catalog: ITM1319
- Gene/Protein: prmt1
- Product Description: Immunotag™ PRMT1 mouse mAb
405.0000
Price in reward points: 405
| Antibody Specification | |
| Datasheet | 
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| Target Protein | PRMT1 |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB |
| Recommended Dilution | wb 1:1000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Mouse |
| Immunogen | Purified recombinant human PRMT1 protein fragments expressed in E.coli. |
| Specificity | This antibody detects endogenous levels of PRMT1 and does not cross-react with related proteins. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | prmt1 |
| Accession No. | Q99873 Q9JIF0 |
| Alternate Names | ANM 1;ANM1;ANM1_HUMAN;complete cds;HCP 1;HCP1;Heterogeneous nuclear ribonucleoprotein methyltransferase 1 like 2;Heterogeneous nuclear ribonucleoproteins methyltransferase like 2;Heterogeneous nuclear ribonucleoproteins methyltransferase like2;Histone-arginine N-methyltransferase PRMT1;HMT 2;HMT1 (hnRNP methyltransferase;HMT1 (hnRNP methyltransferase S. cerevisiae) like 2;HMT1 hnRNP methyltransferase;HMT1 hnRNP methyltransferase like 2 (S. cerevisiae);HMT1 hnRNP methyltransferase like 2;HMT1 hnRNP methyltransferase-like 2 (S. cerevisiae);HMT2;HRMT1 L2;HRMT1L 2;HRMT1L2;Human mRNA for suppressor for yeast mutant;Human mRNA for suppressor for yeast mutant complete cds;Interferon receptor 1 bound protein 4;Interferon receptor 1 bound protein4;Interferon receptor 1-bound protein 4;Interferon receptor 1bound protein 4;IR1 B4;IR1B 4;IR1B4;Mrmt 1;Mrmt1;PRMT 1;PRMT1;Protein arginine methyltransferase 1;Protein arginine N methyltransferase 1;Protein arginine N methyltransferase1;Protein arginine N-methyltransferase 1;R1B4;S. cerevisiae like 2. |
| Description | protein arginine methyltransferase 1(PRMT1) Homo sapiens This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2011], |
| Protein Expression | Glial cell,Lung, |
| Subcellular Localization | nucleus,nucleoplasm,cytoplasm,cytosol,methylosome, |
| Protein Function | enzyme regulation:By BTG1, BTG2 and ILF3.,function:Methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in a glycine and arginine-rich domain (may methylate HNRNPA1 and histones). Methylates SUPT5H and EWS.,similarity:Belongs to the protein arginine N-methyltransferase family.,subunit:Homodimer and heterodimer with PRMT8. The dimer can then associate to form a homohexamer. Interacts with ILF3, BTG1, BTG2, SUPT5H and interferon-alpha/beta receptor 1. Interacts with NFATC2IP., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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