ITM1330
ITM1330
- Catalog: ITM1330
- Gene/Protein: rab4a-n
- Product Description: Immunotag™ RAB4A mouse mAb
405.0000
Price in reward points: 405
| Antibody Specification | |
| Datasheet | 
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| Target Protein | RAB 4A |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB |
| Recommended Dilution | wb 1:500 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat,Monkey |
| Host Species | Mouse |
| Immunogen | Purified recombinant human RAB4A protein fragments expressed in E.coli. |
| Specificity | This antibody detects endogenous levels of RAB4A and does not cross-react with related proteins. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | rab4a-n |
| Accession No. | P20338 P56371 |
| Alternate Names | HRES 1 / RAB4;Oncogene RAB4;OTTHUMP00000042824;Rab 4;RAB 4A;RAB4 member RAS oncogene family;RAB4A;RAB4A member RAS oncogene family;RAB4A_HUMAN;Ras related protein Rab 4A;Ras related protein Rab4A;Ras-related protein Rab-4A. |
| Description | RAB4A, member RAS oncogene family(RAB4A) Homo sapiens This gene is a member of the largest group in the Ras superfamily of small GTPases, which regulate membrane trafficking. The encoded protein is associated with early endosomes and is involved in their sorting and recycling. The protein also plays a role in regulating the recycling of receptors from endosomes to the plasma membrane. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012], |
| Cell Pathway/ Category | Endocytosis, |
| Protein Expression | Brain,Caudate nucleus,Cervix carcinoma,Human small intestine,Skin,U |
| Subcellular Localization | intracellular,endosome,cytosol,plasma membrane,vesicle,insulin-responsive compartment,intracellular membrane-bounded organelle,perinuclear region of cytoplasm,recycling endosome,extracellular exosome, |
| Protein Function | function:Protein transport. Probably involved in vesicular traffic.,PTM:Phosphorylated by CDC2 kinase during mitosis.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Generally associated with membranes. Cytoplasmic when phosphorylated by CDC2.,subunit:Interacts with RAB11FIP1, RABEP1, ZFYVE20 and RUFY1. Interacts with SGSM1, SGSM2 and SGSM3., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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