ITM3084
ITM3084
- Catalog: ITM3084
- Gene/Protein: LALBA
- Product Description: Immunotag™ alpha Lactalbumin Monoclonal Antibody(9E9)
405.0000
Price in reward points: 405
| Antibody Specification | |
| Datasheet | 
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| Target Protein | α-Lactalbumin |
| Clonality | Monoclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,IF, |
| Recommended Dilution | WB: 1:1000 IF 1:200 IHC 1:50-300 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Mouse |
| Immunogen | Synthetic Peptide of alpha Lactalbumin |
| Specificity | The antibody detects endogenous alpha Lactalbumin proteins. |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen |
| Form | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
| Gene Name | LALBA |
| Accession No. | P00709 P29752 P00714 |
| Alternate Names | Alpha-lactalbumin (Lactose synthase B protein) (Lysozyme-like protein 7) |
| Description | lactalbumin alpha(LALBA) Homo sapiens This gene encodes alpha-lactalbumin, a principal protein of milk. Alpha-lactalbumin forms the regulatory subunit of the lactose synthase (LS) heterodimer and beta 1,4-galactosyltransferase (beta4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transfering galactose moieties to glucose. As a monomer, alpha-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. A folding variant of alpha-lactalbumin, called HAMLET, likely induces apoptosis in tumor and immature cells. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Galactose metabolism, |
| Protein Expression | Brain,Milk, |
| Subcellular Localization | Golgi membrane,extracellular space,Golgi lumen, |
| Protein Function | function:Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins.,similarity:Belongs to the glycosyl hydrolase 22 family.,subunit:Lactose synthase (LS) is a heterodimer of a catalytic component, beta1,4-galactosyltransferase (beta4Gal-T1) and a regulatory component, alpha-lactalbumin (LA).,tissue specificity:Mammary gland specific. Secreted in milk., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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