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ITM3379

ITM3379
ITM3379-2
ITM3379
ITM3379-2
ITM3379
  • Catalog: ITM3379
  • Gene/Protein: GAP43
  • Product Description: Immunotag™ GAP-43 Monoclonal Antibody(Mix)
405.0000
Price in reward points: 405

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Immunotag™ GAP-43 Monoclonal Antibody(Mix)
Antibody Specification
Datasheet
Target Protein GAP-43 (Mix)
Clonality Monoclonal
Storage/Stability -20°C/1 year
Application WB,IHC-p
Recommended Dilution WB: 1:1000-2000 IHC:1:200-500
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Mouse
Immunogen Recombinant Protein of GAP-43
Specificity The antibody detects endogenous GAP-43 protein.
Purification The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen
Form PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Gene Name GAP43
Accession No. P17677 P06837 P07936
Alternate Names GAP43; Neuromodulin; Axonal membrane protein GAP-43; Growth-associated protein 43; Neural phosphoprotein B-50; pp46
Description growth associated protein 43(GAP43) Homo sapiens The protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Protein Expression Alzheimer cortex,Brain,Subthalamic nucleus,
Subcellular Localization cytoplasm,plasma membrane,postsynaptic density,cell junction,axon,filopodium membrane,growth cone membrane,
Protein Function function:This protein is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons.,online information:Gap-43 entry,PTM:Phosphorylation of this protein by a protein kinase C is specifically correlated with certain forms of synaptic plasticity.,similarity:Belongs to the neuromodulin family.,similarity:Contains 1 IQ domain.,subcellular location:Cytoplasmic surface of growth cone and synaptic plasma membranes.,subunit:Binds calmodulin with a greater affinity in the absence of Ca(2+) than in its presence.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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