ITM3405
ITM3405
- Catalog: ITM3405
- Gene/Protein: CACNG5
- Product Description: Immunotag™ L-type Ca++ CP γ5 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | L-type Ca++ CP γ5 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p |
Recommended Dilution | WB: 1:500-1000 IHC: 1:100-200 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthetic Peptide of L-type Ca++ CP γ5 |
Specificity | The antibody detects endogenous L-type Ca++ CP γ5 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
Gene Name | CACNG5 |
Accession No. | Q9UF02 Q8VHW4 Q8VHW8 |
Alternate Names | CACNG5; Voltage-dependent calcium channel gamma-5 subunit; Neuronal voltage-gated calcium channel gamma-5 subunit; Transmembrane AMPAR regulatory protein gamma-5; TARP gamma-5 |
Description | calcium voltage-gated channel auxiliary subunit gamma 5(CACNG5) Homo sapiens The protein encoded by this gene is a type II transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type I TARP and a calcium channel gamma subunit. This gene is a susceptibility locus for schizophrenia and bipolar disorder. [provided by RefSeq, Dec 2010], |
Cell Pathway/ Category | MAPK_ERK_Growth,MAPK_G_Protein,Cardiac muscle contraction,Hypertrophic cardiomyopathy (HCM),Arrhythmogenic right ventricular cardiomyopathy (ARVC),Dilated cardiomyopathy, |
Protein Expression | Brain cortex,Thalamus, |
Subcellular Localization | plasma membrane,postsynaptic density,cell junction,AMPA glutamate receptor complex,postsynaptic membrane, |
Protein Function | function:Thought to stabilize the calcium channel in an inactivated (closed) state.,similarity:Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.,subunit:The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |