ITM3559
ITM3559
- Catalog: ITM3559
- Gene/Protein: KCNK10
- Product Description: Immunotag™ KCNK10 (TREK-2) Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | KCNK10 (TREK-2) |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p |
| Recommended Dilution | WB 1:1000-2000, IHC 1:100-200 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Rat,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthetic Peptide of KCNK10 (TREK-2) |
| Specificity | KCNK10(TREK-2) protein(A237) detects endogenous levels of KCNK10(TREK-2) |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | KCNK10 |
| Accession No. | P57789 Q9JIS4 |
| Alternate Names | Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit) |
| Description | potassium two pore domain channel subfamily K member 10(KCNK10) Homo sapiens The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations, and is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Sep 2008], |
| Protein Expression | Brain,Cerebellum,Kidney,Pancreas,Pooled tissue, |
| Subcellular Localization | plasma membrane,integral component of plasma membrane,integral component of membrane, |
| Protein Function | function:Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents. Activated by arachidonic acid and other naturally occurring unsaturated free fatty acids.,similarity:Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.,tissue specificity:Abundantly expressed in pancreas and kidney and to a lower level in brain, testis, colon, and small intestine. Isoform b is strongly expressed in kidney (primarily in the proximal tubule) and pancreas, whereas isoform c is abundantly expressed in brain., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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