ITM6032
ITM6032
- Catalog: ITM6032
- Gene/Protein: KRT15 KRTB
- Product Description: Immunotag™ Cytokeratin 15 (ABT-CK15) mouse mAb
490.0000
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Antibody Specification | |
Datasheet | |
Target Protein | CK-15 (5A1) |
Clonality | Monoclonal |
Storage/Stability | -20°C/1 year |
Application | IHC-p,WB |
Recommended Dilution | IHC-p 1:100-500,WB 1:500-2000 |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Mouse |
Immunogen | Synthesized peptide derived from human Cytokeratin 15 |
Specificity | This antibody detects endogenous levels of human Cytokeratin 15 |
Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | KRT15 KRTB |
Accession No. | P19012 |
Alternate Names | Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15) |
Description | keratin 15(KRT15) Homo sapiens The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region on chromosome 17q21.2. [provided by RefSeq, Jul 2008], |
Protein Expression | Pancreas,Tongue, |
Subcellular Localization | Cytoplasmic, Membranous |
Protein Function | miscellaneous:There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).,similarity:Belongs to the intermediate filament family.,subunit:Heterotetramer of two type I and two type II keratins.,tissue specificity:Expressed in a discontinuous manner in the basal cell layer of adult skin epidermis, but continuously in the basal layer of fetal skin epidermis and nail. Also expressed in the outer root sheath above the hair bulb in hair follicle (at protein level). Expressed homogeneously in all cell layers of the esophagus and exocervix, but detected in the basal cell layer only of oral mucosa, skin and in the basal plus the next two layers of the suprabasal epithelium of the palate., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |