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ITN0076

ITN0076
  • Catalog: ITN0076
  • Gene/Protein: LSM1 CASM
  • Product Description: Immunotag™ LSM1 Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ LSM1 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein LSM1
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human,Mouse
Host Species Rabbit
Immunogen Synthesized peptide derived from human protein . at AA range: 50-130
Specificity LSM1 Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name LSM1 CASM
Accession No. O15116 Q8VC85
Description LSM1 homolog, mRNA degradation associated(LSM1) Homo sapiens This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Nov 2011],
Cell Pathway/ Category RNA degradation,
Protein Expression Eye,Lymph node,
Subcellular Localization cytoplasmic mRNA processing body,nucleus,cytoplasm,cytosol,axon,dendrite,neuronal cell body,messenger ribonucleoprotein complex,
Protein Function function:Binds specifically to the 3'-terminal U-tract of U6 snRNA.,similarity:Belongs to the snRNP Sm proteins family.,subunit:LSm subunits form a heteromer with a donut shape.,tissue specificity:Has elevated expression in pancreatic cancer and in several cancer-derived cell lines.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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