ITN0076
ITN0076
- Catalog: ITN0076
- Gene/Protein: LSM1 CASM
- Product Description: Immunotag™ LSM1 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | LSM1 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from human protein . at AA range: 50-130 |
Specificity | LSM1 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | LSM1 CASM |
Accession No. | O15116 Q8VC85 |
Description | LSM1 homolog, mRNA degradation associated(LSM1) Homo sapiens This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Nov 2011], |
Cell Pathway/ Category | RNA degradation, |
Protein Expression | Eye,Lymph node, |
Subcellular Localization | cytoplasmic mRNA processing body,nucleus,cytoplasm,cytosol,axon,dendrite,neuronal cell body,messenger ribonucleoprotein complex, |
Protein Function | function:Binds specifically to the 3'-terminal U-tract of U6 snRNA.,similarity:Belongs to the snRNP Sm proteins family.,subunit:LSm subunits form a heteromer with a donut shape.,tissue specificity:Has elevated expression in pancreatic cancer and in several cancer-derived cell lines., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |